Comparison of Two Commercial In-Vitro Maturation Culture Systems with Standard IVM Media: What Works Best for Mouse Oocytes

Background: Despite many variations made to the standard IVM protocol and to the culture conditions the rate of implantation ranges between 5% to 22% and the pregnancy rate ranges from around 8% to 40% [1]. The culture media is important as it provides the oocyte with vital metabolites such as ATP and pyruvate [2]. In order to improve the success rates with IVM, many changes have been made to the standard IVM media and studies have emerged that compare the various components of the IVM media based on maturation, developmental and fertilization rates of immature oocytes.